PT  - JOURNAL ARTICLE
AU  - Bloch, H M
AU  - Thornton, J R
AU  - Heaton, K W
TI  - Effects of fasting on the composition of gallbladder bile.
AID  - 10.1136/gut.21.12.1087
DP  - 1980 Dec 01
TA  - Gut
PG  - 1087--1089
VI  - 21
IP  - 12
4099  - http://gut.bmj.com/content/21/12/1087.short
4100  - http://gut.bmj.com/content/21/12/1087.full
SO  - Gut1980 Dec 01; 21
AB  - Gallbladder bile was aspirated from the duodenum in nine healthy women after three separate periods of fasting after a standardised meal. Mean cholesterol saturation index was significantly greater after a 15 hour fast (1.35 +/- 0.08) than after a 10 hour fast (1.05 +/- 0.10). However, after 20 hours of fasting, mean cholesterol saturation index had fallen to 1.13 +/- 0.10. Total biliary lipid concentration was unaffected. These findings suggest that fasting has a series of effects on gallbladder bile and that bile sampling should be carried out at at standardised period of time after the last meal.