RT Journal Article
SR Electronic
T1 Effect of secretogogues on mucosal blood flow in the antrum and corpus of the stomach.
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 14
OP 18
DO 10.1136/gut.19.1.14
VO 19
IS 1
A1 Taylor, T V
A1 Pullan, B R
A1 Goddard, J
A1 Torrance, B
YR 1978
UL http://gut.bmj.com/content/19/1/14.abstract
AB Gastric mucosal blood flow in the rat was determined by the indicator fractionation technique of Sapirstein using Rb86Cl. Antral and corpus flow rates were determined in response to increasing doses of pentagastrin and histamine and the effect of vagotomy was determined. With progressive stimulation the antral:corpus flow ratio increased with both stimulants; however, vagotomy and noradrenaline reduced blood flow in both areas of mucosa. It is concluded that the antrum, as well as the corpus, actively responds to secretory stimulants by an increase in mucosal blood flow and support is provided for the theory that the antrum plays an active role in the control of parietal cell blood flow and secretion.