RT Journal Article
SR Electronic
T1 Effect of sodium taurocholate on gastric secretion in patients with duodenal ulceration
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 28
OP 32
DO 10.1136/gut.24.1.28
VO 24
IS 1
A1 M R Lewin
A1 E Pifano
A1 R D Daniel
A1 P B Boulos
A1 C G Clark
YR 1983
UL http://gut.bmj.com/content/24/1/28.abstract
AB The effect of sodium taurocholate instillation on the stimulated stomachs of patients with duodenal ulceration has been investigated. Instillation into the stomach of sodium taurocholate significantly reduced pentagastrin stimulated volume and outputs of both acid and sodium, with no change in the calculated volume of duodenogastric reflux. These observations are not consistent with the back-diffusion theory, but suggest direct parietal cell inhibition of gastric secretion by sodium taurocholate.