PT - JOURNAL ARTICLE AU - F Raul AU - R Noriega AU - E Nsi-Emvo AU - M Doffoel AU - J F Grenier TI - Lactase activity is under hormonal control in the intestine of adult rat. AID - 10.1136/gut.24.7.648 DP - 1983 Jul 01 TA - Gut PG - 648--652 VI - 24 IP - 7 4099 - http://gut.bmj.com/content/24/7/648.short 4100 - http://gut.bmj.com/content/24/7/648.full SO - Gut1983 Jul 01; 24 AB - In the adult rat, starvation during 48 hours led to a three fold increase of lactase specific activity in the intestinal brush border membranes. Thyroxine injection during the three days before death (0.5 micrograms/g daily) inhibited the stimulation of lactase activity induced by starvation without modifying sucrase activity whereas hydrocortisone injections (25 micrograms/g daily) or thyroidectomy did not modify the stimulatory effect of starvation on lactase activity. These results suggests a specific hormonal control of intestinal lactase activity in the rat.