RT Journal Article
SR Electronic
T1 Gold induced enterocolitis.
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 452
OP 456
DO 10.1136/gut.27.4.452
VO 27
IS 4
A1 Jackson, C W
A1 Haboubi, N Y
A1 Whorwell, P J
A1 Schofield, P F
YR 1986
UL http://gut.bmj.com/content/27/4/452.abstract
AB A case of gold associated enterocolitis is described. A review of all 27 previously reported cases revealed that the syndrome induced has common characteristics. The reaction occurs within three months of instituting gold therapy, is characterised by profuse diarrhoea and vomiting with abdominal pain, fever, and sometimes eosinophilia. Petechial changes are prominent on endoscopy and the endoscopic and histological features of the gut lesion do not resemble inflammatory bowel disease. The overall mortality is 26% but has decreased in recent years. There is no specific therapy but in severe cases diversional surgery may be justified.