RT Journal Article
SR Electronic
T1 Glucagonoma syndrome demonstrating giant duodenal villi.
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 784
OP 791
DO 10.1136/gut.25.7.784
VO 25
IS 7
A1 F M Stevens
A1 R W Flanagan
A1 D O'Gorman
A1 K D Buchanan
YR 1984
UL http://gut.bmj.com/content/25/7/784.abstract
AB A 39 year old man developed an itchy bullous rash in the perineum and on the extremities. Six years later, after giant intestinal villi had been noted at endoscopy, a diagnosis of the glucagonoma syndrome was made. Investigation revealed a large tumour of the pancreatic body and tail. The molecular species of glucagon secreted by the tumour were characterised using the combined purification procedures of immunoaffinity chromatography followed by gel filtration.