RT Journal Article SR Electronic T1 Twenty four hour manometric recording of colonic motor activity in healthy man. JF Gut JO Gut FD BMJ Publishing Group Ltd and British Society of Gastroenterology SP 17 OP 25 DO 10.1136/gut.28.1.17 VO 28 IS 1 A1 F Narducci A1 G Bassotti A1 M Gaburri A1 A Morelli YR 1987 UL http://gut.bmj.com/content/28/1/17.abstract AB The motor activity of the transverse, descending, and sigmoid colon was recorded for 24 hours in 14 healthy volunteers with a colonoscope positioned catheter. During the study the patients ate two 1000 kcal mixed meals and one continental breakfast. Colonic motor activity was low before meals and minimal during sleep; the motility index increased significantly after meals and at morning awakening. Most of the motor activity was represented by low amplitude contractions present singly or in bursts, which showed no recognisable pattern. All but two subjects also showed isolated high amplitude (up to 200 mmHg) contractions that propagated peristaltically over long distances at approximately 1 cm/sec. Most of these contractions occurred after morning awakening, and some in the late postprandial period, with a mean of 4.4/subject/24 h. The peristaltic contractions were often felt as an urge to defecate or preceded defecation, and could represent the manometric equivalent of the mass movements.