PT  - JOURNAL ARTICLE
AU  - M E Baca
AU  - A M Mowat
AU  - S MacKenzie
AU  - D M Parrott
TI  - Functional characteristics of intraepithelial lymphocytes from mouse small intestine. III. Inability of intraepithelial lymphocytes to induce a systemic graft-versus-host reaction is because of failure to migrate in vivo.
AID  - 10.1136/gut.28.10.1267
DP  - 1987 Oct 01
TA  - Gut
PG  - 1267--1274
VI  - 28
IP  - 10
4099  - http://gut.bmj.com/content/28/10/1267.short
4100  - http://gut.bmj.com/content/28/10/1267.full
SO  - Gut1987 Oct 01; 28
AB  - In this study we have investigated whether addition of bone marrow accessory cells or concurrent administration of recombinant IL-2 would allow intraepithelial lymphocytes (IEL) to induce a systemic, lethal GvHR in irradiated hosts. In addition we have studied the ability of IEL to migrate into lymphoid tissues after intravenous injection and compared this with their locomotor capacity in vitro.