PT - JOURNAL ARTICLE AU - D L Morris AU - J B Chinnery AU - G Georgiou AU - G Stamatakis AU - B Golematis TI - Penetration of albendazole sulphoxide into hydatid cysts. AID - 10.1136/gut.28.1.75 DP - 1987 Jan 01 TA - Gut PG - 75--80 VI - 28 IP - 1 4099 - http://gut.bmj.com/content/28/1/75.short 4100 - http://gut.bmj.com/content/28/1/75.full SO - Gut1987 Jan 01; 28 AB - The penetration of albendazole sulphoxide, the principal metabolite of albendazole into hydatid cysts (E granulosus) was measured by means of in vitro animal and clinical studies. The drug freely diffuses across the parasitic membranes. Cyst/serum concentrations of 22% were achieved in patients, longer pre-operative therapy produced higher concentrations.