PT  - JOURNAL ARTICLE
AU  - P R Mills
AU  - R N MacSween
AU  - H M Dick
AU  - W S Hislop
TI  - Histocompatibility antigens in patients with alcoholic liver disease in Scotland and northeastern England: failure to show an association.
AID  - 10.1136/gut.29.2.146
DP  - 1988 Feb 01
TA  - Gut
PG  - 146--148
VI  - 29
IP  - 2
4099  - http://gut.bmj.com/content/29/2/146.short
4100  - http://gut.bmj.com/content/29/2/146.full
SO  - Gut1988 Feb 01; 29
AB  - A study of HLA-A and B antigens in 248 patients with biopsy diagnosed alcoholic liver disease was conducted to examine for a genetic predisposition to alcohol related liver injury. No statistically significant differences were established for 8 HLA-A and 16 HLA-B antigens between normal healthy controls (n = 342) and patients with alcoholic fatty liver (n = 86), alcoholic hepatitis (n = 63), active alcoholic cirrhosis (n = 64) and inactive alcoholic cirrhosis (n = 35). It is concluded that no HLA-A or B locus genetic susceptibility to alcoholic related injury could be shown.