PT  - JOURNAL ARTICLE
AU  - R J Ede
AU  - K P Moore
AU  - W J Marshall
AU  - R Williams
TI  - Frequency of pancreatitis in fulminant hepatic failure using isoenzyme markers.
AID  - 10.1136/gut.29.6.778
DP  - 1988 Jun 01
TA  - Gut
PG  - 778--781
VI  - 29
IP  - 6
4099  - http://gut.bmj.com/content/29/6/778.short
4100  - http://gut.bmj.com/content/29/6/778.full
SO  - Gut1988 Jun 01; 29
AB  - Evidence of acute pancreatitis was sought in 35 patients with fulminant hepatic failure. Total amylase was raised in 22 patients and isoenzyme separation showed a distinct P3 isoenzyme (indicative of pancreatitis) in 14. In four patients with marked hyperamylasaemia (greater than 1000 U/l) the predominant isoenzyme was the salivary fraction. Pancreatic lipase was abnormally raised (greater than 200 U/l) in 34 patients but exceeded 1000 U/l in 12 of the 14 with a distinct P3 isoenzyme. Thus on the basis of a distinct P3 isoenzyme of amylase and an increased pancreatic lipase activity evidence of pancreatitis was found in 34% of patients in this series.