RT Journal Article SR Electronic T1 Sufotidine 600 mg bd virtually eliminates 24 hour intragastric acidity in duodenal ulcer subjects. JF Gut JO Gut FD BMJ Publishing Group Ltd and British Society of Gastroenterology SP 291 OP 293 DO 10.1136/gut.31.3.291 VO 31 IS 3 A1 Smith, J T A1 Pounder, R E YR 1990 UL http://gut.bmj.com/content/31/3/291.abstract AB In a double blind study, 24 hour intragastric acidity and 24 hour plasma gastrin concentrations were measured simultaneously in seven duodenal ulcer subjects on the fifth day of receiving either sufotidine 600 mg bd or placebo. Compared with placebo, during treatment with sufotidine 600 mg bd the median integrated 24 hour intragastric acidity was decreased by 95% (range 74% to 99%) from 1000 to 51 mmol/h/l, whilst the median integrated 24 hour plasma gastrin concentration increased from 416 to 927 pmol/h/l.