RT Journal Article
SR Electronic
T1 Interaction of campylobacter species with antibody, complement and phagocytes.
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 906
OP 911
DO 10.1136/gut.30.7.906
VO 30
IS 7
A1 E Bernatowska
A1 P Jose
A1 H Davies
A1 M Stephenson
A1 D Webster
YR 1989
UL http://gut.bmj.com/content/30/7/906.abstract
AB The opsonisation of four different campylobacter species for human neutrophils was studied using a chemiluminescence system and electron microscopy. Opsonisation of Campylobacter fetus, Campylobacter coli, and Campylobacter jejuni was mediated by antibody and enhanced by complement. Antibody was not, however, required for the phagocytosis of Campylobacter pylori because it activates the classical pathway of complement directly. This unusual property may be important in the pathogenesis of C pylori associated gastritis and duodenal ulcer.