TY - JOUR T1 - Treatment of chronic hepatitis C with recombinant interferon alfa-2b. JF - Gut JO - Gut SP - S128 LP - S129 DO - 10.1136/gut.34.2_Suppl.S128 VL - 34 IS - 2 Suppl AU - M Piazza AU - R Orlando AU - G Tosone AU - D Tiseo AU - M C Conte AU - F Minervini AU - G Santoro AU - F Scordino AU - D Vitale Y1 - 1993/01/01 UR - http://gut.bmj.com/content/34/2_Suppl/S128.abstract N2 - In a study of 87 patients with chronic hepatitis C, 12 months' treatment with interferon alfa-2b at a dose of 6 million units (MU) three times per week seemed to be more effective than treatment with 3 MU three times a week for two months plus 1.5 MU three times a week for 10 months in increasing the percentage of long term responders. The percentage of patients in whom alanine amino-transferase activities returned to normal was highest in the 6 MU group, as was the percentage of responders who sustained this normal activity after treatment. Side effects were moderate and self-limited in most patients. ER -