PT  - JOURNAL ARTICLE
AU  - M Moretó
AU  - M Zaballa
AU  - M J Suárez
AU  - S Ibáñez
AU  - E Ojembarrena
AU  - J M Castillo
TI  - Endoscopic local injection of ethanolamine oleate and thrombin as an effective treatment for bleeding duodenal ulcer: a controlled trial.
AID  - 10.1136/gut.33.4.456
DP  - 1992 Apr 01
TA  - Gut
PG  - 456--459
VI  - 33
IP  - 4
4099  - http://gut.bmj.com/content/33/4/456.short
4100  - http://gut.bmj.com/content/33/4/456.full
SO  - Gut1992 Apr 01; 33
AB  - The injection of a mixture of ethanolamine oleate and thrombin as an effective treatment for bleeding duodenal ulcer was evaluated in 38 patients entered in a randomised prospective controlled trial. After a one week observation period, 1/19 (5.3%) treated patients and 11/19 (57.9%) control patients had suffered further bleeding (p less than 0.005; CI = 22%-74%). Emergency surgery was required in 1/19 in the treated group compared with 8/19 in the untreated group (CI = 13%-61%; p less than 0.05). The mean (SD) transfusion requirement in the treated group was 1.9 (0.5) U blood compared with 5.3 (0.7) U in the control group. No significant differences related to mortality were detected. In conclusion, local injection therapy is an effective means of haemostasis in patients with bleeding duodenal ulcer who are at risk of further bleeding.