TY - JOUR T1 - Copper associated childhood cirrhosis. JF - Gut JO - Gut SP - 1497 LP - 1500 DO - 10.1136/gut.35.10.1497 VL - 35 IS - 10 AU - S P Horslen AU - M S Tanner AU - T D Lyon AU - G S Fell AU - M F Lowry Y1 - 1994/10/01 UR - http://gut.bmj.com/content/35/10/1497.abstract N2 - Several papers have reported severe liver disease in association with massive hepatic copper accumulation, which do not seem to be either of the recognised copper associated liver diseases, namely Wilson's disease and Indian childhood cirrhosis. A further case is reported in which novel copper kinetic studies were carried out using the stable isotope 65Cu, showing that this patient did not suffer from Wilson's disease. It is suggested that these cases can be divided into two groups on the basis of age, clinical course, and history of excessive copper ingestion. The benefits of using 65Cu for in vivo studies of copper metabolism is discussed. ER -