PT - JOURNAL ARTICLE AU - M Frisoni AU - G R Corazza AU - D Lafiandra AU - E De Ambrogio AU - C Filipponi AU - F Bonvicini AU - E Borasio AU - E Porceddu AU - G Gasbarrini TI - Wheat deficient in gliadins: promising tool for treatment of coeliac disease. AID - 10.1136/gut.36.3.375 DP - 1995 Mar 01 TA - Gut PG - 375--378 VI - 36 IP - 3 4099 - http://gut.bmj.com/content/36/3/375.short 4100 - http://gut.bmj.com/content/36/3/375.full SO - Gut1995 Mar 01; 36 AB - The toxicity of two varieties of bread wheat, one poor in alpha and beta gliadins and the other poor in alpha, beta, gamma, and omega gliadins, has been tested. The peptic-tryptic digest of these wheats was assessed using coeliac mucosa in an in vitro organ culture system. A significantly lower toxicity was found in respect of bread wheat containing all gliadin fractions. These results suggest new opportunities for the treatment of coeliac disease.