RT Journal Article
SR Electronic
T1 Diversion colitis: a trigger for ulcerative colitis in the in-stream colon?
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 279
OP 282
DO 10.1136/gut.44.2.279
VO 44
IS 2
A1 A G Lim
A1 F L Langmead
A1 R M Feakins
A1 D S Rampton
YR 1999
UL http://gut.bmj.com/content/44/2/279.abstract
AB The aetiology of ulcerative colitis is unknown. Two patients without pre-existing inflammatory bowel disease in whom end colostomy for faecal incontinence was complicated by diversion colitis in the defunctioned rectosigmoid colon, are described. In both instances, colitis with the clinical, colonoscopic, and microscopic features of ulcerative colitis developed about a year later in the previously normal in-stream colon proximal to the colostomy. These cases suggest that diversion colitis may be a risk factor for ulcerative colitis in predisposed individuals and that ulcerative colitis can be triggered by anatomically discontinuous inflammation elsewhere in the large intestine.ANAantinuclear antibodypANCAperinuclear antineutrophilic cytoplasmic antibody