PT  - JOURNAL ARTICLE
AU  - S Ohashi
AU  - K Segawa
AU  - S Okamura
AU  - M Mitake
AU  - H Urano
AU  - M Shimodaira
AU  - T Takeda
AU  - S Kanamori
AU  - T Naito
AU  - K Takeda
AU  - B Itoh
AU  - H Goto
AU  - Y Niwa
AU  - T Hayakawa
TI  - The utility of endoscopic ultrasonography and endoscopy in the endoscopic mucosal resection of early gastric cancer
AID  - 10.1136/gut.45.4.599
DP  - 1999 Oct 01
TA  - Gut
PG  - 599--604
VI  - 45
IP  - 4
4099  - http://gut.bmj.com/content/45/4/599.short
4100  - http://gut.bmj.com/content/45/4/599.full
SO  - Gut1999 Oct 01; 45
AB  - OBJECTIVE To clarify the usefulness of endoscopic ultrasonography (EUS) and endoscopy in the endoscopic mucosal resection (EMR) of early gastric cancer.Patients/Methods—EMR was performed in 61 patients with early gastric cancer over the past five years. The accuracy of the assessment of the depth of cancerous invasion was studied in 49 patients who had EUS before EMR. Forty eight patients were treated with endoscopy alone; in these patients, EUS and endoscopic findings correlated with the clinical course.RESULTS Forty six patients showed no changes in the submucosal layer or deeper structures on EUS. Pathologically these included 37 patients with mucosal cancer and nine with submucosal cancer showing very slight submucosal infiltration. Three patients showed diffuse low echo changes in the submucosal layer on EUS; pathologically, these included two with submucosal cancer and one with mucosal cancer with a peptic ulcer scar within the tumour focus. Of 48 patients receiving endoscopic treatment alone, 45 showed no tumour recurrence or evidence of metastases on EUS and endoscopy. Three cases of recurrence were observed. Two of these patients had a surgical gastrectomy, and one was re-treated endoscopically. In the former cases, the surgical results correlated well with assessment by EUS and endoscopy. In addition, the latter patient who was re-treated endoscopically after evaluation with EUS and endoscopy has so far had no recurrence.CONCLUSION The combined use of EUS and endoscopy is effective in diagnosing the depth of cancerous invasion in patients undergoing EMR as well as in clarifying changes both within and between anatomic levels during follow up.EUSendoscopic ultrasonographyEMRendoscopic mucosal resection