TY - JOUR T1 - Effects of short term sacral nerve stimulation on anal and rectal function in patients with anal incontinence JF - Gut JO - Gut SP - 407 LP - 412 DO - 10.1136/gut.44.3.407 VL - 44 IS - 3 AU - C J Vaizey AU - M A Kamm AU - I C Turner AU - R J Nicholls AU - J Woloszko Y1 - 1999/03/01 UR - http://gut.bmj.com/content/44/3/407.abstract N2 - BACKGROUND Some patients with faecal incontinence are not amenable to simple surgical sphincter repair, due to sphincter weakness in the absence of a structural defect.AIMS To evaluate the efficacy and possible mode of action of short term stimulation of sacral nerves in patients with faecal incontinence and a structurally intact external anal sphincter.PATIENTS Twelve patients with faecal incontinence for solid or liquid stool at least once per week.METHODS A stimulating electrode was placed (percutaneously in 10 patients, operatively in two) into the S3 or S4 foramen. The electrode was left in situ for a minimum of one week with chronic stimulation.RESULTS Evaluable results were obtained in nine patients, with early electrode displacement in the other three. Incontinence ceased in seven of nine patients and improved notably in one; one patient with previous imperforate anus and sacral agenesis had no symptomatic response. Stimulation seemed to enhance maximum squeeze pressure but did not alter resting pressure. The rectum became less sensitive to distension with no change in rectal compliance. Ambulatory studies showed a possible reduction in rectal contractile activity and diminished episodes of spontaneous anal relaxation.CONCLUSIONS Short term sacral nerve stimulation notably decreases episodes of faecal incontinence. The effect may be mediated via facilitation of striated sphincter muscle function, and via neuromodulation of sacral reflexes which regulate rectal sensitivity and contractility, and anal motility.EMGelectromyographyPNEpercutaneous nerve evaluation ER -