TY - JOUR T1 - Scintigraphic validation of a magnetic resonance imaging method to study gastric emptying of a solid meal in humans JF - Gut JO - Gut SP - 106 LP - 111 DO - 10.1136/gut.44.1.106 VL - 44 IS - 1 AU - C Feinle AU - P Kunz AU - P Boesiger AU - M Fried AU - W Schwizer Y1 - 1999/01/01 UR - http://gut.bmj.com/content/44/1/106.abstract N2 - Background We have previously used a magnetic resonance imaging (MRI) method to study gastric emptying of liquids. So far, however, it has not possible to assess solid gastric emptying with this technique.Aims To validate scintigraphically MRI as a method for measuring emptying of a mixed solid/liquid meal.Methods In eight healthy subjects, gastric emptying of a solid/liquid (SM) and a liquid meal (LM) of identical energy content and macronutrient composition was studied by scintigraphy and MRI for 120 minutes.Results MRI and scintigraphy agreed with respect to emptying profiles (intraclass correlation coefficient (RI) SM: 0.988, RI, LM: 0.917), t1/2 (SMMRI: 129 (9), SMScinti: 123 (11) minutes, NS; LMMRI: 100 (7), LMScinti: 110 (8) minutes, NS) and AUC (SMMRI: 8999 (232), SMScinti: 8788 (277) min%, NS; LMMRI: 8819 (368), LMScinti: 8891 (321) min%, NS).Conclusions MRI can be used to measure reliably gastric emptying not only of liquid but also of mixed solid/liquid meals in humans.MRImagnetic resonance imagingGd-DOTAgadolinium tetraazacyclododecane tetraacetic acidAUCarea under the curveRIintraclass correlation coefficient ER -