RT Journal Article
SR Electronic
T1 A case of primary low grade mucosa associated lymphoid tissue (MALT) lymphoma of the oesophagus
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 281
OP 284
DO 10.1136/gut.51.2.281
VO 51
IS 2
A1 S Hosaka
A1 N Nakamura
A1 T Akamatsu
A1 T Fujisawa
A1 Y Ogiwara
A1 K Kiyosawa
A1 E Hidaka
A1 H Ota
A1 T Katsuyama
A1 H Inagaki
YR 2002
UL http://gut.bmj.com/content/51/2/281.abstract
AB We report a very rare case of primary low grade mucosa associated lymphoid tissue (MALT) lymphoma of the oesophagus. An 83 year old woman was referred to our hospital in June 1999 for further examination and treatment of oesophageal tumour. Although a physical examination and laboratory data showed no significant abnormalities, endoscopic observation revealed two slightly elevated submucosal tumour-like lesions of the oesophagus. Tissue specimens were obtained by endoscopic mucosal resection of the oesophagus using a cap fitted panendoscope. The lesions were composed of diffuse small atypical lymphoid cells—that is, centrocyte-like cells—which were stained with CD20, L26, BCL-2, and κ, but not with CD3, CD5, CD10, or cyclin D1. Monoclonality was detected by polymerase chain reaction analysis using the primer for CDR-3 of immunoglobulin H and diagnosed as low grade MALT lymphoma of the oesophagus. The tumours were considered to be completely resected and therefore additional treatment was not administered. The patient is alive and well 22 months after treatment and diagnosis.