RT Journal Article
SR Electronic
T1 On the use of tritium-labelled albumin for studies of intestinal absorption
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 346
OP 352
DO 10.1136/gut.5.4.346
VO 5
IS 4
A1 K. N. Jeejeebhoy
A1 J. H. Stewart
A1 E. A. Evans
A1 C. C. Booth
YR 1964
UL http://gut.bmj.com/content/5/4/346.abstract
AB Human serum albumin has been successfully labelled with tritium. It is considerably denatured in the process and has a shorter half life when given intravenously than 131I-labelled albumin. Nevertheless it is satisfactory for absorption studies, although not for turnover observations. These studies on absorption in control subjects and in patients with intestinal malabsorption indicate that the excreted radioactivity may have been derived from endogenous sources rather than from the results of malabsorption alone.