TY - JOUR T1 - Cryptic gluten intolerance in type 1 diabetes: identifying suitable candidates for a gluten free diet JF - Gut JO - Gut SP - 133 LP - 134 DO - 10.1136/gut.2005.077511 VL - 55 IS - 1 AU - D Sblattero AU - A Ventura AU - A Tommasini AU - L Cattin AU - S Martelossi AU - F Florian AU - R Marzari AU - A Bradbury AU - T Not Y1 - 2006/01/01 UR - http://gut.bmj.com/content/55/1/133.abstract N2 - Long term exposure to gluten in coeliacs,1 and coeliac disease (CD) diagnosis after 16 years of age2 may induce type 1 diabetes (T1D) and other autoimmune disorders. Increased prevalence of CD among diabetics and their relatives is well documented.3 Early introduction of gluten to children at high risk for T1D produces T1D associated islet autoantibodies.4 Similarly, in the absence of overt clinical symptoms of T1D, some coeliac children produce diabetes autoantibodies in a gluten dependent manner.5 In diabetics, intestinal challenge with gluten produces mucosal recruitment of lymphocytes,6 similar to that in CD patients.7 In diabetics, however, there is no production of CD related anti-tissue transglutaminase antibodies (anti-tTG).6 We have used a phage display assay8 to show that in CD patients, production of anti-tTG is limited to the intestine. Here, we … ER -