RT Journal Article SR Electronic T1 Management of Helicobacter pylori infection—the Maastricht IV/ Florence Consensus Report JF Gut JO Gut FD BMJ Publishing Group Ltd and British Society of Gastroenterology SP 646 OP 664 DO 10.1136/gutjnl-2012-302084 VO 61 IS 5 A1 Peter Malfertheiner A1 Francis Megraud A1 Colm A O'Morain A1 John Atherton A1 Anthony T R Axon A1 Franco Bazzoli A1 Gian Franco Gensini A1 Javier P Gisbert A1 David Y Graham A1 Theodore Rokkas A1 Emad M El-Omar A1 Ernst J Kuipers A1 The European Helicobacter Study Group (EHSG) YR 2012 UL http://gut.bmj.com/content/61/5/646.abstract AB Management of Helicobacter pylori infection is evolving and in this 4th edition of the Maastricht consensus report aspects related to the clinical role of H pylori were looked at again in 2010. In the 4th Maastricht/Florence Consensus Conference 44 experts from 24 countries took active part and examined key clinical aspects in three subdivided workshops: (1) Indications and contraindications for diagnosis and treatment, focusing on dyspepsia, non-steroidal anti-inflammatory drugs or aspirin use, gastro-oesophageal reflux disease and extraintestinal manifestations of the infection. (2) Diagnostic tests and treatment of infection. (3) Prevention of gastric cancer and other complications. The results of the individual workshops were submitted to a final consensus voting to all participants. Recommendations are provided on the basis of the best current evidence and plausibility to guide doctors involved in the management of this infection associated with various clinical conditions.