TY - JOUR T1 - A challenging case of multiple splenic and pancreatic lesions in a patient with Crohn's disease JF - Gut JO - Gut SP - 295 LP - 295 DO - 10.1136/gutjnl-2015-310130 VL - 65 IS - 2 AU - G Boschetti AU - S Assaad AU - B Balme AU - S Boyer AU - B Flourié AU - S Nancey Y1 - 2016/02/01 UR - http://gut.bmj.com/content/65/2/295.abstract N2 - A 40-year-old woman with a history of ileocolonic Crohn's disease treated with oral mesalamine presented with fever and diffuse abdominal pain without diarrhoea. Laboratory tests were notable only for increased serum C-reactive protein (CRP) (46 mg/L) and leucocytosis (10 100 cells/μL) with neutrophilia (8700 cells/μL). Abdominal CT revealed multiple mesenteric lymph nodes (MLNs) without evidence of thickening of the bowel wall or complications such as stricture, fistula or abscess. Laparoscopic biopsy samples of some MLNs were performed; their histopathological analysis revealed a suppurative lymphadenitis, with a strong infiltration by neutrophils, oedema and tissue necrosis without granuloma or identification of any micro-organisms, including alcohol acid-resistant bacilli (AARB). Three … ER -