RT Journal Article SR Electronic T1 Diagnosis and management of acute lower gastrointestinal bleeding: guidelines from the British Society of Gastroenterology JF Gut JO Gut FD BMJ Publishing Group Ltd and British Society of Gastroenterology SP 776 OP 789 DO 10.1136/gutjnl-2018-317807 VO 68 IS 5 A1 Kathryn Oakland A1 Georgina Chadwick A1 James E East A1 Richard Guy A1 Adam Humphries A1 Vipul Jairath A1 Simon McPherson A1 Magdalena Metzner A1 A John Morris A1 Mike F Murphy A1 Tony Tham A1 Raman Uberoi A1 Andrew McCulloch Veitch A1 James Wheeler A1 Cuthbert Regan A1 Jonathan Hoare YR 2019 UL http://gut.bmj.com/content/68/5/776.abstract AB This is the first UK national guideline to concentrate on acute lower gastrointestinal bleeding (LGIB) and has been commissioned by the Clinical Services and Standards Committee of the British Society of Gastroenterology (BSG). The Guidelines Development Group consisted of representatives from the BSG Endoscopy Committee, the Association of Coloproctology of Great Britain and Ireland, the British Society of Interventional Radiology, the Royal College of Radiologists, NHS Blood and Transplant and a patient representative. A systematic search of the literature was undertaken and the quality of evidence and grading of recommendations appraised according to the GRADE(Grading of Recommendations Assessment, Development and Evaluation) methodology. These guidelines focus on the diagnosis and management of acute LGIB in adults, including methods of risk assessment and interventions to diagnose and treat bleeding (colonoscopy, computed tomography, mesenteric angiography, endoscopic therapy, embolisation and surgery). Recommendations are included on the management of patients who develop LGIB while receiving anticoagulants (including direct oral anticoagulants) or antiplatelet drugs. The appropriate use of blood transfusion is also discussed, including haemoglobin triggers and targets.