RT Journal Article
SR Electronic
T1 International consensus conference on stool banking for faecal microbiota transplantation in clinical practice
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 2111
OP 2121
DO 10.1136/gutjnl-2019-319548
VO 68
IS 12
A1 Giovanni Cammarota
A1 Gianluca Ianiro
A1 Colleen R Kelly
A1 Benjamin H Mullish
A1 Jessica R Allegretti
A1 Zain Kassam
A1 Lorenza Putignani
A1 Monika Fischer
A1 Josbert J Keller
A1 Samuel Paul Costello
A1 Harry Sokol
A1 Patrizia Kump
A1 Reetta Satokari
A1 Stacy A Kahn
A1 Dina Kao
A1 Perttu Arkkila
A1 Ed J Kuijper
A1 Maria J GT Vehreschild
A1 Cristina Pintus
A1 Loris Lopetuso
A1 Luca Masucci
A1 Franco Scaldaferri
A1 E M Terveer
A1 Max Nieuwdorp
A1 Antonio López-Sanromán
A1 Juozas Kupcinskas
A1 Ailsa Hart
A1 Herbert Tilg
A1 Antonio Gasbarrini
YR 2019
UL http://gut.bmj.com/content/68/12/2111.abstract
AB Although faecal microbiota transplantation (FMT) has a well-established role in the treatment of recurrent Clostridioides difficile infection (CDI), its widespread dissemination is limited by several obstacles, including lack of dedicated centres, difficulties with donor recruitment and complexities related to regulation and safety monitoring. Given the considerable burden of CDI on global healthcare systems, FMT should be widely available to most centres.Stool banks may guarantee reliable, timely and equitable access to FMT for patients and a traceable workflow that ensures safety and quality of procedures. In this consensus project, FMT experts from Europe, North America and Australia gathered and released statements on the following issues related to the stool banking: general principles, objectives and organisation of the stool bank; selection and screening of donors; collection, preparation and storage of faeces; services and clients; registries, monitoring of outcomes and ethical issues; and the evolving role of FMT in clinical practice,Consensus on each statement was achieved through a Delphi process and then in a plenary face-to-face meeting. For each key issue, the best available evidence was assessed, with the aim of providing guidance for the development of stool banks in order to promote accessibility to FMT in clinical practice.