TY - JOUR T1 - Response to the letter to the editor JF - Gut JO - Gut SP - 840 LP - 840 DO - 10.1136/gutjnl-2021-324887 VL - 71 IS - 4 AU - Ji Young Bang AU - Robert Hawes AU - Shyam Varadarajulu Y1 - 2022/04/01 UR - http://gut.bmj.com/content/71/4/840.1.abstract N2 - We would like to thank Tehami et al 1 for their interest in our work2 and would like to address the caveats that they have outlined in their letter. One, the statement ‘a definitive diagnosis could be established in 2/21 patients in the endoscopic ultrasound (EUS)-guided group’ is incorrect. A definitive diagnosis could be established in 2/21 patients only with cumulative assessment of both biopsy passes; in 19 others, a diagnosis was made on a single pass. Two, the authors state that this yield contradicts previously published diagnostic rates of 93.9%—however, a diagnosis was established in 100% of subjects in our study. Three, the authors debate the exclusion of patients with alternative diagnosis made at EUS from this trial. Per protocol, if EUS identified alternative aetiologies for elevated liver … ER -