Table 4

Density of innervation in regions of the sigmoid colon in controls and in patients with idiopathic megarectum and idiopathic megacolon

Longitudinal muscle Circular muscle Muscularis mucosae Lamina propria
Controls
 S1001  (0–3)4  (4)3  (0–3)3  (0–3)
 PGP 9.52 (0–3)4 (4)3 (0, 3)3 (0, 3)
Idiopathic megarectum
 S1001 (0–3)4 (3–5)2 (0–3)2 (0–3)
 PGP 9.51 (0–2)7-150 4 (3–5)3 (0–3)3 (0–3)
Idiopathic megacolon
 S1001 (0–2)7-150 4 (3–5)3 (0–3)3 (0–3)
 PGP 9.51 (0–3)3.5 (3–4)3 (2–3)3 (2–3)
  • Values given are median (range) score. Scoring system: 0, absent; 1, very sparse; 2, sparse; 3, moderate; 4, dense; 5, very dense. Tissues from three control patients and patients with idiopathic megarectum and those with idiopathic megacolon, all of whom had a dilated proximal colon.

  • 7-150 p<0.05.