Localisation and positive rate of immunoreactivity of inducible nitric oxide synthase in colonic tissues in patients with active ulcerative colitis
| Grades 2 and 3 (n = 17) | Grades 4 and 5 (n = 16) | ||||||
|---|---|---|---|---|---|---|---|
| Quiescent mucosa | Actively inflamed mucosa | Quiescent mucosa | Actively inflamed mucosa | ||||
| Negative | 16 (94) | 8 (47) | 15 (94) | 0 (0) | |||
| Epithelium only | 0 (0) | 0 (0) | 0 (0) | 2 (12) | |||
| Lamina propria only | 1 (6) | 6 (35) | 0 (0) | 3 (19) | |||
| Both epithelium and lamina propria | 0 (0) | 3 (19) | 1 (6) | 11 (69) | |||
Values in parentheses are percentages.
Staining of inducible nitric oxide synthase was compared in quiescent and actively inflamed colonic mucosa of patients with ulcerative colitis. The histological grade was divided into mild or moderate inflammation (grade 2 or 3) and severe inflammation (grade 4 or 5).