Table 3

Prevalence of upper dyspepsia (UD) in 1982, incidence of UD in 1987 and seroprevalence of IgG antibodies to H pylori in 1982: crude and multivariate adjusted odds ratios (OR)5-152 by UD definitions5-150

UD definitions5-150 and IgG antibody status n (%) Unadjusted OR5-152 Sex and age adjusted OR5-152 Multivariate adjusted OR5-152 95% CI5-151
Colin-Jones’ definition
UD prevalence (1982)
 IgG seronegative940  (47.4)
 IgG borderline320 (47.4)0.991.041.02(0.84–1.24)
 IgG seropositive455 (49.0)–1.35)
UD incidence (1987)
 IgG seronegative154 (17.5)
 IgG borderline60 (20.5)1.281.381.17(0.78–1.75)
 IgG seropositive75 (19.5)1.131.321.37(0.96–1.97)
Talley’s definition
UD prevalence (1982)
 IgG seronegative465 (36.4)
 IgG borderline157 (36.5)1.030.891.02(0.80–1.30)
 IgG seropositive225 (37.3)–1.21)
UD incidence (1987)
 IgG seronegative75 (12.0)
 IgG borderline34 (17.3)1.231.371.28(0.86–1.91)
 IgG seropositive37 (13.8)1.201.441.46(1.02–2.10)
Authors’ definition
UD prevalence (1982)
 IgG seronegative991 (49.9)
 IgG borderline346 (51.2)–1.34)
 IgG seropositive478 (51.5)–1.23)
UD incidence (1987)
 IgG seronegative181 (21.6)
 IgG borderline63 (23.2)1.051.621.15(0.80–1.65)
 IgG seropositive102 (27.9)1.421.231.71(1.24–2.36)
  • 5-150 See text for definition.

  • 5-151 95% Confidence intervals for multivarite adjusted odds ratios.

  • 5-152 The upper odds ratio represents the risk of having the symptom in IgG borderline cases compared with IgG seronegative people. The lower odds ratio is the corresponding risk in IgG seropositive people compared with IgG seronegative people.