Specimen site | Pathological condition | Treatment | Isc (μA/cm2) | PD (mV) | G (mS/cm2) |
Small bowel | |||||
Non-IBD | Cl+ | 79.0 (28.0) | 3.6 (1.2) | 21.5 (2.8) | |
Cl− | 27.9 (12.2) | 2.0 (0.7) | 13.5 (2.9) | ||
Crohn’s disease | Cl+ | 63.9 (8.0) | 3.4 (0.5) | 23.0 (2.5) | |
Cl− | 33.3 (5.6)* | 2.7 (0.4) | 14.2 (0.9)* | ||
Large bowel | |||||
Non-IBD | Cl+ | 140.0 (36.4) | 15.2 (3.2) | 8.7 (0.7) | |
Cl− | 60.6 (11.1)* | 15.1 (2.2) | 7.4 (0.4) | ||
Crohn’s disease | Cl+ | 156.8 (24.1) | 13.2 (4.1) | 22.4 (6.0) | |
Cl− | 74.1 (22.2)* | 9.7 (3.7) | 18.3 (5.6) | ||
Ulcerative colitis | Cl+ | 49.7 (9.9) | 5.0 (1.0) | 9.9 (0.8) | |
Cl− | 17.8 (4.8)* | 3.3 (0.5) | 4.1 (1.2)* |
Values are mean (SEM), n = 3–7 subjects per group with equal numbers of tissues treated with chloride containing buffer (Cl+) or chloride free buffer (Cl−). *p<0.05 compared with Cl+.