Table 7

Clinical and laboratory features and their relation to the presence or absence of prostaglandin producing suppressor cells (PPSC) in vitro

Independent variable	Evidence of PPSC	No evidence of PPSC	Statistical significance
Age (mean (SD))	42.9 (18.0)	47.8 (18.2)	p>0.05^13-150
Sex (M/F)	20/24	20/31	p=0.684^†
Bilirubin
⩾10×	15	20
<10×	29	31	p=0.761^†
AP
⩾5×	29	21
<5×	13	30	p=0.525^†
GGT
⩾8×	22	24
<8×	22	27	p=0.936^†
ALT
⩾10×	15	30
<10×	29	21	p=0.027^†
AST
⩾10×	19	36
<10×	25	15	p=0.012^†
Eosinophilia (Y/N)	18/26	15/36	p=0.338^†
Latency time
⩽10 days	19	10
>10 days	22	40	p=0.014^†
Remission time
⩽60 days	29	21
>60 days	13	30	p=0.013^†
Pattern
Cholestatic	16	21
Hepatocellular	20	19	p=0.717^‡
Mixed	8	11
Pharmacological group
Antimicrobial	13	12
NSAID/analgesic	3	16
Psychotropic	5	11	p=0.017^‡
Antihypertensive	10	1
Other	13	11

↵13-150 Student’s t test; ^†two tail Fisher’s exact test; ^‡χ² test; AP, alkaline phosphatase; GGT, γ-glutamyltranspeptidase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; NSAID, non-steroidal anti-inflammatory drug.
Laboratory values are expressed in multiples of the upper limits of normal.