Classes of daily alcohol consumption of the screened population (n=6534), expressed as absolute number (n) and percentage of lines (%), according to the presence of either non-cirrhotic alcohol-induced liver damage (NCLD) or cirrhosis or hepatocellular carcinoma (=cirrhosis)
Alcohol intake (g/day) | No (n=6442) | NCLD (n=57) | Cirrhosis (n=35) | Multivariate analysis (odds ratio) (95% CI) | |||||
---|---|---|---|---|---|---|---|---|---|
For NCLDa | For cirrhosisa | ||||||||
Teetotallers | 2501 (99.9) | 0 (0) | 1 (0.04) | — | — | ||||
0.1–30 | 2666 (99.3) | 13 (0.5) | 4 (0.15) | —b | —b | ||||
31–60 | 745 (97.2) | 14 (1.8) | 8 (1.0) | 7.5 (3.5 to 15.9) | 10.9 (3.6 to 33.5) | ||||
61–90 | 276 (93.0) | 14 (4.7) | 7 (2.3) | 20.2 (9.4 to 43.3) | 25.0 (7.9 to 79.3) | ||||
91–120 | 132 (91.6) | 5 (3.5) | 7 (4.9) | 15.1 (5.3 to 42.8) | 52.9 (16.6 to 169) | ||||
>120 | 122 (86.5) | 11 (7.8) | 8 (5.7) | 35.8 (15.7 to 81.6) | 62.3 (20.1 to 193) |
Anti-HCV and HbsAg positive subjects (n=313), and 70 subjects in whom either the food questionnaire or the blood tests were not completed were also excluded.
aIn order to calculate odds ratio and 95% confidence intervals (CI), all the groups that showed statistical significance for the presence of either NCLD or cirrhosis at the multivariate analysis (that is, people drinking more than 30 g/day) were compared with the teetotallers and the moderate drinkers (<30 g/day) grouped together. Above this threshold limit p was always less than 0.00001.
bp v teetotallers, not significant.