Table 1

Effect of R093877 on stool frequency and consistency

R093877 1 mg (n=8) Placebo (n=8) p Value R093877 2 mg (n=7) Placebo (n=7) p Value
Days urge to defaecate1-150
Days stool passed1-150
No of stools/week13.67.80.00312.18.50.10
Stools loose/watery1-150 61.524.20.03744.010.30.011
  • 1-150 Expressed as per cents. For the 2 mg dose, the non-compliant volunteer has been excluded.