Comparison of bowel frequency and stool consistency in the week after active drug and placebo were given
| Week after R093877 1 mg (n=8) | Week after placebo (n=8) | p Value | Week after R093877 2 mg (n=7) | Week after placebo (n=7) | p Value | |
| Days urge to defaecate3-150 | 83.9 | 91.1 | 0.42 | 76.8 | 76.8 | 0.99 |
| Days stool passed3-150 | 82.1 | 89.3 | 0.4 | 73.2 | 71.4 | 0.65 |
| No of stools/week | 8 | 7.9 | 0.87 | 8.4 | 7 | 0.4 |
| Stools loose/watery3-150 | 10.9 | 9.5 | 0.9 | 5.2 | 3.8 | 0.33 |
↵3-150 Expressed as per cents. For the 2 mg dose, the non-compliant volunteer has been excluded.