Table 2

Genotypes of NAT in intestinal samples

Sample		NAT1		PABA activity (nmol/min/mg protein)		NAT2		SMZ activity (nmol/min/mg protein)
Sample		NAT1		PABA activity (nmol/min/mg protein)		Genotype	Phenotype	SMZ activity (nmol/min/mg protein)
A (11/5)	1^4, 1^4	6.1 (0.2)	2^4, 2^5B	FS	0.85 (0.01)
B (18/5)	1^4, 1^14	2.1 (0.1)	2^4, 2^4	FF	1.18 (0.03)
C (22/3)	1^4, 1^4	6.9 (0.3)	2^5B, 2^6A	SS	0.22 (0.02)
D (24/3)	1^4, 1^4	7.5 (0.1)	2^5B, 2^5B	SS	0.23 (0.01)

The names of alleles are as described in Vatsis et al.¹⁰ The phenotype of NAT2 has been determined from the genotype and is shown to indicate fast alleles as ‘F’ and slow alleles as ‘S’. Activities with sulphamethazine (SMZ) orp-aminobenzoic acid (PABA) are the values for the most proximal section of intestine in each case and are the mean (SD) of four individual estimations.