Table 1

Phenotype of intraepithelial (IEL) and lamina propria (LPL) T lymphocytes from normal human gut

T cell markers1-150
Cell suspension CD4+ CD8+ CD4+CD8+ CD4CD8 CD69+
Duodenum
 IEL12% (5–21)76% (50–93)5% (3–12) 14% (3–32)96% (92–100)
 LPL45% (30–74)62% (45–71)6% (0–14) 7% (5–15) 93% (86–97)
Colon
 IEL46% (21–55)50% (31–61)3% (1–5)17% (8–32) 83% (65–90)
 LPL46% (41–53)48% (30–56)3% (2–3)17% (12–20) 76% (72–80)
  • 1-150 Expressed as percentages of CD3+ cells. Results obtained by flow cytometric analysis are shown as medians (ranges). Triple immunofluorescence allowed counting of both the CD3+/CD4+/CD8+ and the CD3+/CD4/CD8 lymphocytes.