Table 1

Helicobacter pylori strains used in this study

Strain^1-150 no.		Protein secretion		Vacuolating assay		Type^1-151
Strain^1-150 no.		VacA	CagA	Vacuolating assay		Type^1-151
Gastric ulcer
1	(T-1)	+	+	+	I
2	(T-6)	+	+	+	I
3	(T-24)	+	+	+	I
4	(T-39)	+	+	+	I
5	(T-72)	+	+	+	I
6	(T-84)	+	+	+	I
7	(T-97)	+	+	+	I
8	(T-23)	+	+	+	I
9	(T-59)	+	+	+	I
10	(T-78)	+	+	+	I
11	(T-99)	+	+	+	I
12	(T-48)	−	+	+	I
13	(T-87)	−	+	+	I
14	(T-79)	+	+	−	Intermediate
15	(T-98)	+	+	−	Intermediate
16	(T-57)	+	−	−	Intermediate
Duodenal ulcer
17	(T-10)	+	+	+	I
18	(T-29)	+	+	+	I
19	(T-54)	+	+	+	I
20	(T-56)	+	+	+	I
21	(T-60)	+	+	+	I
22	(T-71)	+	+	+	I
23	(T-74)	+	+	+	I
24	(T-92)	+	+	+	I
25	(T-101)	+	+	+	I
26	(T-9)	+	+	+	I
27	(T-13)	+	+	+	I
28	(T-35)	+	+	+	I
29	(T-63)	+	+	+	I
30	(T-82)	+	+	+	I
31	(T-12)	−	−	+	Intermediate
32	(T-64)	+	−	−	Intermediate
33	(T-15)	−	+	−	Intermediate
Non-ulcer dyspepsia
34	(T-5)	+	+	+	I
35	(T-11)	+	+	+	I
36	(T-17)	+	+	+	I
37	(T-61)	+	+	+	I
38	(T-75)	+	+	+	I
39	(T-76)	+	+	+	I
40	(T-77)	+	+	+	I
41	(T-80)	+	+	+	I
42	(T-89)	+	+	+	I
43	(T-90)	+	+	+	I
44	(T-111)	+	+	+	I
45	(T-16)	+	+	+	I
46	(T-73)	+	+	+	I
47	(T-88)	+	+	+	I
48	(T-93)	+	+	+	I
49	(T-100)	+	+	+	I
50	(T-102)	+	+	+	I
51	(T-103)	+	+	+	I
52	(T-94)	+	−	+	Intermediate
53	(T-53)	+	−	+	Intermediate
54	(T-47)	+	+	−	Intermediate
55	(T-3)	−	+	−	Intermediate
56	(T-25)	−	−	−	II
57	(T-85)	−	−	−	II
58	(T-68)	−	−	−	II
Gastric cancer
59	(T-7)	+	+	+	I
60	(T-115)	+	+	+	I
61	(T-116)	+	+	+	I
62	(T-22)	+	+	+	I
63	(T-26)	+	+	+	I
64	(T-81)	+	+	+	I
65	(T-112)	+	+	+	I
66	(T-113)	+	+	+	I
67	(T-114)	+	+	+	I
68	(T-108)	−	+	−	Intermediate
Controls
69	(43526)	+	+	+
70	(Tx30a)	+	−	−

↵1-150 The strains whose designation starts with a T were isolated at Tokyo University Hospital. 43526 was ATCC 43526 from American Type Culture Collection and Tx30a was from Texas.
↵1-151 Type I strains were positive for vacuolating activity and CagA protein. Type II strains were negative for both, and intermediate strains belonged to neither Type I nor Type II.