Table 2

Ethanol induced gastric mucosal damage: the effect of sensory ablation and sialoadenectomy. Microscopic assessment (grade 3 damage; mean (SEM) %)

Intact innervation Sensory ablation
Sham operation
 Solvent27.5  (3.4)21.3 (4.2)
 EGF10.7 (3.6)3-150 27.5 (7.2)
 Capsaicin4.3 (2.1)3-150 32.5 (3.7)
 Capsaicin + EGF7.5 (3.1)3-150 28.2 (9.0)
Sialoadenectomy
 Solvent25.1 (6.8)33.8 (3.5)
 EGF16.0 (4.1)36.5 (5.4)
 Capsaicin2.5 (2.5)3-150 31.7 (5.7)
 Capsaicin + EGF7.8 (3.1)3-150 25.5 (4.5)
  • 3-150 p < 0.05 versus respective solvent groups; p < 0.05 versus respective intact innervation groups.