Clinical improvement as a function of the presence or absence of one or more highly threatening chronic difficulties during the previous 10 months
| One or more highly threatening chronic difficulty | ||
| Clinical improvement5-150 | Absent (%)5-151 | Present (%)5-152 |
| Absent | 24 | 35 |
| Present | 41 | 0 |
↵5-150 Defined as the presence or absence of a 50% or more improvement in symptom intensity at 16 months.
↵5-151 In the cohort without highly threatening chronic difficulties, the relative risk of no clinical improvement vclinical improvement was 0.4 (95% CI 0.3 to 0.5).
↵5-152 In the cohort with highly threatening chronic difficulties, the relative risk of no clinical improvement vclinical improvement could not be calculated as none of the patients exposed to this stressor improved by 50% or more.