Table 1

HFE genotypes in healthy controls and patients with different histological severities of alcoholic liver disease (ALD)

Number of cases (%)
HFE genotype Fibrotic ALD Alcoholic hepatitis No hepatitis Fatty liver Controls
Wild type homozygote148  (61.1)58  (61.1)69  (60.0)8  (53.3)66  (56.4)
H63D heterozygote47 (19.4)20 (21.1)23 (20.0)3 (20)33 (28.2)
H63D homozygote7 (2.9)3 (3.1)3 (2.6)1 (0.85)
C282Y heterozygote31 (12.8)11 (11.5)14 (12.1)2 (13.3)15 (12.8)
C282Y, H63D heterozygote7 (2.9)2 (2.1)5 (4.3)1(6.6)1 (0.85)
C282Y homozygote2 (0.83)1 (1.1)1 (0.9)1 (6.6)1 (0.85)
Total242 (100)95 (100)115 (100)15 (100)117 (100)
  • Fibrotic ALD includes patients with cirrhosis and precirrhotic fibrosis.