Table 4

Mean total LI and number of mitoses per crypt for known gene carriers and known non-gene carriers

Controls HNPCC 50% risk p Value7-150
Site Mean LI Mean no of mitoses Mean LI Mean no of mitoses Mean LI Mean no of mitoses
Rectum0.33 (0.05)5.7 (1.20)0.33 (0.04)4.6 (0.66)0.970.36
Sigmoid0.32 (0.03)7.9 (2.17)0.38 (0.05)5.8 (0.77)0.380.33
Descending colon0.36 (0.04)7.1 (1.30)0.41 (0.04)5.9 (0.87)0.450.45
Transverse colon0.34 (0.04)7.0 (1.34)0.39 (0.04)5.5 (0.60)0.400.29
Ascending colon0.38 (0.04)7.0 (0.89)0.43 (0.04)7.0 (0.93)0.440.97
  • Results are expressed as mean (SEM).

  • 7-150 Controls v HNPCC 50% risk. Due to concern related to repeated significance testing, p>0.01 was considered non-significant.