Crypt depth (μm) to villous height (μm) ratios, and individual measurements—blood flow in villous tips beginning to slow
| Control villus | Test villus | ||
| 1 | Crypt depth | 24.7 | 20.9 |
| Villous height | 57 | 55.1 | |
| Ratio | 0.42 | 0.38 | |
| 2 | Crypt depth | 22.8 | 19 |
| Villous height | 57 | 51.3 | |
| Ratio | 0.4 | 0.37 | |
| 3 | Crypt depth | 20.9 | 19 |
| Villous height | 51.3 | 47.5 | |
| Ratio | 0.41 | 0.4 | |
| 4 | Crypt depth | 17.1 | 17.1 |
| Villous height | 47.5 | 57 | |
| Ratio | 0.36 | 0.3 | |
| 5 | Crypt depth | 20.9 | 19 |
| Villous height | 60.8 | 57 | |
| Ratio | 0.34 | 0.33 |
The measurements were made from perfuse fixed villi exposed to luminal (100 μg/ml) and an intravenous bolus dose of indomethacin estimated to produce a plasma concentration of 100 μg/ml where blood flow in the villous tips was beginning to slow.