Table 2

Oxidative stress markers in controls and patients at admission

Healthy controls Mild acute pancreatitis Severe acute pancreatitis
Chemiluminescence (CL) (count/10 sec)383.5  (35.2)1129.6  (120.4)** 2381.9  (232.0)**
CL/PMN (count/10 sec/mm3)0.11 (0.01)0.20 (0.04)0.23 (0.02)**
Total ascorbic acid (TAA) (mg/l)11.5 (0.4)3.4 (0.4)** 2.2 (0.3)**
DHAA:TAA (%)17.4 (4.0)66.8 (5.2)** 74.7 (6.8)**
α- Tocopherol (mg/l)10.5 (1.2)10.1 (0.2)9.6 (0.4)3-150
 (mg/g TL)2.01 (0.02)1.97 (0.04)1.90 (0.04)3-150
TBARS (nmol/ml)2.3 (0.1)4.0 (0.4)** 6.2 (0.4)**
  • Values are means (SEM).

  • 3-150 p<0.05; **p<0.01 v controls; p<0.01 vmild acute pancreatitis.

  • PMN, polymorphonuclear leucocytes; DHAA, dehydroascorbic acid; TL, plasma total lipids; TBARS, thiobarbituric acid reactive substances.