Glutathione status in peripheral blood mononuclear cells (PMBC) in IBD
| rGSH (nmol/mg protein) | GSSG (nmol/mg protein) | rGSH/GSSG | |
| Control (n=65) | 22.8 (1.2) | 2.05 (0.11) | 12.2 (0.8) |
| Crohn’s disease (n=33) | |||
| Before surgery | 23.0 (2.0) | 2.06 (0.17) | 14.7 (2.0) |
| 10 days after surgery | 20.2 (1.4) | 2.23 (0.21) | 11.8 (1.5) |
| 3 months after surgery | 22.2 (1.5) | 2.19 (0.20) | 12.0 (1.2) |
| Ulcerative colitis (n=33) | |||
| Before surgery | 19.5 (1.3) | 2.25 (0.24) | 11.5 (1.3) |
| 10 days after surgery | 17.9 (1.3) | 2.43 (0.25) | 10.0 (1.2) |
| 3 months after surgery | 20.7 (1.1) | 2.30 (0.20) | 11.0 (1.1) |
Values are expressed as mean (SE). Data were analysed using the Student’s t test for unpaired samples. Significance was set at p<0.008, according to Bonferroni’s correction.