Table 1

Clinical, biochemical, immunological, and histological features at presentation in the 21 patients with type 2 autoimmune hepatitis

Patient Age (y) Sex Autoantibodies ALT (× normal) AST (× normal) Albumin (g/l) γ Globulin (g/l) IgG (g/l) Liver histology IAHG score
113FLC1107.5284057Severe CAH19d
27FLKM12014NA3033.2Severe CAH19d
39FLC1156461419.2Severe CAH16p
510MLKM1/LC185421724.1Severe CAH15p
65FLC13530NANANAActive cirrhosis19d
79FLKM144453639Active cirrhosis20d
98FLKM1107314839.7Active cirrhosis20d
1018FLKM18070431524.5Severe CAH18d
1120FLC117114028NASevere CAH18d
124FLC16070352331Severe CAH16p
133FLKM1/LC11519294049.9Active cirrhosis19d
1410MLKM1/LC1324519NAActive cirrhosis16p
161FLKM14069NANANASevere CAH19d
178FLC13540NA3624.8Severe CAH18d
185FLC11520441421Severe CAH18d
2014FLKM1/LC120NA353850Severe CAH19d
2130FLKM154402625.8Severe CAH18d
  • ALT, serum alanine aminotransferase; AST, serum aspartate aminotransferase; LC1, liver cytosol antibody type 1; LKM1, liver/kidney microsomal antibody type 1; NA, not available; CAH, chronic active hepatitis; MN, multilobular necrosis; IAHG, International Autoimmune Hepatitis Group; d, definite autoimmune hepatitis; p, probable autoimmune hepatitis.