Subject | Gender M/F | Time of diagnosis | Age (years) | HFE | Screening | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age (years) | Mobilised storage iron (g) | C282Y | H63D | Haemoglobin (mmol/l) | Serum iron (μmol/l) | TIBC (μmol/l) | Saturation of TIBC (%) | Serum ferritin (μg/l) | AST (U/l) | ALT (U/l) | GGT (U/l) | ||||
Tea group | |||||||||||||||
1.1 | M | 19 | 4.2 | 29 | ND | 10.6 | 35.6 | 39.2 | 91 | 119 | 8 | 7 | 5 | ||
1.2 | M | 57 | 23.6 | 67 | ND | 9.1 | 32.8 | 39.8 | 82 | 254 | 26 | 19 | 22 | ||
1.3 | M | 36 | 20.8 | 46 | +/+ | −/− | 11.0 | 42.3 | 45.0 | 94 | 189 | 27 | 29 | 10 | |
1.4 | M | 58 | 3.5 | 60 | ND | 10.7 | 14.9 | 42.4 | 35 | 179 | 20 | 33 | 29 | ||
1.5 | M | 50 | 20.0 | 54 | ND | 9.7 | 38.9 | 53.0 | 73 | 119 | 45 | 55 | — | ||
1.6 | M | 36 | — | 37 | ND | 9.8 | 19.3 | 36.7 | 53 | 137 | 11.2 | 16 | 9.3 | ||
1.71-150 | M | 49 | 5.0 | 52 | +/+ | −/− | 10.6 | 24.0 | 34.4 | 70 | 180 | 65 | 176 | 20 | |
1.8 | M | 42 | 4.8 | 47 | +/+ | −/− | 11.7 | 47.3 | 49.9 | 95 | 61 | 27 | 60 | 37 | |
1.9 | M | 20 | 1.4 | 20 | ND | 10.6 | 21.0 | 69.3 | 30 | 178 | 25 | 55 | 56 | ||
Mean | 9M | 40.8 | 10.4 | 45.8 | 10.4 | 30.6 | 44.6 | 69 | 157 | 28 | 50 | 24 | |||
SEM | 4.5 | 2.9 | 4.7 | 0.2 | 3.6 | 3.8 | 8 | 17 | 5 | 16 | 6 | ||||
Water group | |||||||||||||||
2.1 | M | 37 | 19.6 | 45 | ND | 9.9 | 32.1 | 41.4 | 77 | 301 | 23 | 32 | 14 | ||
2.2 | M | 19 | 4.4 | 26 | +/+ | −/− | 9.2 | 21.5 | 42.2 | 47 | 110 | 10 | 12 | 9 | |
2.3 | M | 27 | 4.6 | 29 | +/+ | −/− | 9.9 | 15.9 | 38.1 | 42 | 151 | 27 | 61 | 12 | |
2.4 | M | 39 | 15.0 | 47 | +/+ | −/− | 10.1 | 30.1 | 43.5 | 69 | 192 | 19 | 13 | — | |
2.5 | F | 71 | 2.4 | 71 | +/+ | −/− | 9.9 | 35.1 | 41.4 | 85 | 600 | 20 | 37 | 12 | |
2.6 | M | 43 | 17.7 | 44 | +/+ | −/− | 8.1 | 18.8 | 55.3 | 30 | 63 | 38 | 55 | 36 | |
2.71-150 | M | 49 | 5.0 | 53 | +/+ | −/− | 10.2 | 24.7 | 48.2 | 51 | 96 | 65 | 176 | 20 | |
2.8 | M | 41 | 23.2 | 44 | +/+ | −/− | 10.2 | 41.6 | 47.8 | 87 | 252 | 42 | 76 | 40 | |
2.9 | M | 39 | 17.1 | 45 | +/+ | −/− | 10.0 | 28.7 | 37.3 | 77 | 180 | 39 | 58 | 19 | |
2.10 | M | 43 | 5.3 | 82 | ND | 8.9 | 32.2 | 42.6 | 76 | 285 | — | 192 | — | ||
Mean | 1F/9M | 40.8 | 11.5 | 46.6 | 9.6 | 28.3 | 44.2 | 64 | 223 | 31 | 71 | 20 | |||
SEM | 4.1 | 2.3 | 4.0 | 0.2 | 2.0 | 1.6 | 6 | 46 | 5 | 19 | 4 |
↵1-150 Patient participating twice.
TIBC, total iron binding capacity; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, γ-glutamyl transpeptidase; ND, not done.