Table 1

Fatigue, sleep and depression in primary biliary cirrhosis

Patients verbally reporting fatigue (n=60) Patients verbally reporting no fatigue (n=28) Normal population controls
Fatigue severity score (FSS)
 Mean (SD)4.56 (1.6)1-150 2.4 (1.2)2.53 (1.18)1-152
 Range1–71–4.7
Global sleep quality (PSQI)
 Mean (SD)8.72 (4.9) 5.07 (3.4)2.67 (1.7)1-153
 Range1–211–16
Depressive symptoms
Observer rated HDRS
 Mean (SD)9.56 (5.4)1-150 2.89 (3.9)61-154
 Range0–280–15
Self rated CES-D
 Mean (SD)11.5 (9.3) 5.12 (5.0)9.25 (8.6)1-160
 Range0–420–18
  • 1-150 p<0.0001, p<0.0005 v patients with PBC verbally reporting no fatigue.

  • 1-152 Schwartz et al.10

  • 1-153 Buysse et al.11

  • 1-154 Hamilton et al.12

  • 1-160 Radloff, 15 maximum of three general population means, 7.94, 8.17, 9.25.13